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Paediatric Laboratory Medicine

Herpes group II PCR (CMV, EBV, HHV6A/B)

Test Name

Herpes group II PCR (CMV, EBV, HHV6A/B)

Alternate Name/ Synonym

Cytomegalovirus, Epstein Barr virus, human herpes virus 6A & 6B

Gene Name


Test Code

H456PC, H456PO, H456PP


Molecular Microbiology - Viral


Real-time Polymerase Chain Reaction

External Proficiency Testing

College of American Pathologists

Turn Around Time

Within 4 days



  • Neonatal infection
  • Encephalitis
  • Disseminated disease
  • Monitoring of transplant patients


  • Reactivation disease
  • Disseminated infection
  • PTLD
  • Monitoring of transplant patients


  • Monitoring of transplant patients

Specimen Type

  • Whole blood
  • Plasma
  • Tissue or biopsy
  • Lower respiratory specimens

Minimum Specimen Requirements

  • Whole blood (EDTA) - 1 mL minimum for 1 test, 3-5 mL recommended for multiple tests
  • Plasma - 0.5 mL minimum for 1 test, >1 mL recommended for multiple tests
  • Sterile screw top container for tissues, biopsies, respiratory specimens      


  • All specimens must be shipped on dry ice
  • Exception: Specimens that will arrive at SickKids within 24 hours from the time of collection can be shipped on ice packs

Special Requirements

* Not Health Canada approved

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Phone: 416-813-7200
Phone: 1-855-381-3212