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Paediatric Laboratory Medicine

Kingella kingae PCR

Clinical Significance

Kingella kingae is an important cause of septic arthritis in young children. Its fastidious nature makes it difficult to culture. K.kingae may also cause bacteria in young children and  endocarditis in children and adults (HACEK group).

Test Name

Kingella kingae PCR

Alternate Name/ Synonym

  • Qualitative
  • Real-time PCR

Gene Name

RTX toxin

Alternate Gene Name

rtxB

Organism

Kingella kingae

Test Code

KINGPC

Division

Molecular Microbiology

External Proficiency Testing

Blind testing, laboratory exchange with Hospital St. Justine

Turn Around Time

Weekly (at least)

Disease/Condition

  • Septic arthritis
  • Endocarditis

Specimen Type

  • Synovial fluid/biopsy
  • Bone biopsy
  • Vegetation (heart valve)

Minimum Specimen Requirements

  • 0.4 mL

Storage/Transportation

  • All specimens must be shipped on dry ice.
  • Exception: specimens that arrive at SickKids within 24hrs from time of collection can be shipped on ice packs.

Therapeutic Range

N/A

Reference Range

Negative. Not detected.

Critical Values

Positive result