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  • Cytogenetics Laboratory
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Cytogenetics Laboratory

The Cytogenetics Laboratory specializes in the genomic analysis of paediatric specimens, referred for a wide range of constitutional conditions and cancer diagnosis and management.

The laboratory has expertise in molecular cytogenetics analysis and offers a large variety of FISH tests.

The Cytogenetics Laboratory currently provides:

• Genomic microarray analysis on an Agilent 180K custom designed platform.  
  • The design is based on the International Standard for Microarray Consortium (ISCA) design. 
  • The oligonucleotide probe coverage is enriched (approximately 20 to 50 kb resolution) in genomic regions associated with known genetic conditions causing developmental delay, mental retardation and/or multiple congenital abnormalities. 
  • The remainder of the euchromatic genome is interrogated with a resolution of approximately 100 kb.
  • Effective March 1st 2011, SickKids will accept specimens for genomic microarray testing. For further information see What’s New.
• Extensive testing for the SickKids Haematology/Oncology program

We are a Children’s Oncology Group (COG)-Approved laboratory. 

The laboratory is unique in the province in having a substantial caseload of specialized testing for the chromosome instability syndromes.