PASSAGING XEN CELLS (EXTRA-EMBRYONIC ENDODERM STEM CELLS)
reference:

Kunath T, Arnaud D, Uy GD, Okamoto I, Chureau C, Yamanaka Y, Heard E, Gardner RL, Avner P, Rossant J.
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts.

Development (2005) 132 (7), 1649-1661.


Medium for XEN Cells
Xen cells may be grown in RPMI medium plus 15% FCS.

Medium:
Medium for XEN Cells
Culture TS cells in the above medium in a standard tissue culture incubator (37oC, 5% CO2 incubator. The cells are passaged (1:20 to 1:40) every 2 to 3 days. If they are split 1:20, they may be confluent in 2-3 day.The media is changed every second day; however, when they reach >60% confluence, the media should be changed daily.