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Adult CNS Vasculitis

Primary and secondary CNS vasculitis 

CNS vasculitis often affects previously healthy patients. If the inflammation solely targets the blood vessels of the brain and/or spinal cord in these patients, the disease is then referred to as primary CNS vasculitis or Primary Angiitis of the CNS (PACNS)

All patients require a careful assessment for an associated systemic illness such as an infection, rheumatic disease or malignancy. Patients who develop CNS vasculitis in the context of an underlying illness are considered to have Secondary CNS Vasculitis.  

CNS Vasculitis tree adult diagram

More information on differential diagnosis and mimics of CNS vasculitis can be found here