For more information, visit:

http://www.sickkids.ca/Endocrinology/index.html

Brief Biography

Farid Mahmud received his medical degree at The University of Alberta, Edmonton. He trained in Paediatric Endocrinology and Metabolism at The Mayo Clinic, Rochester.

He is currently Staff Physician in the Division of Endocrinology, Department of Paediatrics and Assistant Professor at the University of Toronto and Project Investigator at The Hospital for Sick Children Research Institute.

Clinical Care Activities

Dr. Mahmud is involved in care with patients with endocrine disorders, diabetes as well calcium and bone health clinics.

Research Interests

I am a pediatric endocrinologist and clinical investigator with a special interest in the study of diabetes complications. This includes celiac disease in type 1 diabetes as well as the evaluation of early atherosclerosis in young patients with endocrine conditions who are at high risk of cardiovascular disease including, obesity and type 1 and type 2 diabetes. We are also evaluating the impact of Vitamin D on vascular health as well as the impact of novel electronic learning tools in chronic disease care.    

Publications

S. Amed, D Daneman, FH Mahmud & J Hamilton. Type 2 Diabetes in Children & Adolescents. Expert Reviews in Cardiovascular Therapies, 2010.

FH  Mahmud, D Hill, M Cuerdin, C Clarson. Impaired Endothelial Function in Obese Adolescents with Insulin Resistance. Journal of Pediatrics 2009 155 (5): 678-82      

CL Clarson, FH Mahmud, JE Baker, HE Clark, WM Mckay, VD Schauteet & D Hill, Metformin in combination with structured lifestyle intervention improved body mass index in obese adolescents, but did not improve insulin resistance. 2009. Endocrinology 36: 141-146.

M Salvadori, J M. Sontrop, AX.Garg, Jennifer Truong, Rita S. Suri, FH Mahmud,  J J. Macnab, WF. Clark.  Pediatric Hypertension in Relation to Obesity in a Rural Canadian Community. 2008. Pediatrics. Vol. 122 No. 4.  October 2008, pp. e821-e827

Mahmud FH, N Kanji , S. Van Um, C. Clarson.  Endothelial Function is Impaired Both Fasting and After a High-Fat Meal in Adolescents with Type 1 Diabetes Mellitus. Journal of Pediatrics  2008.  152 (4) 557-562   

Celluci T, Zelcer S, Mahmud FH. Polyuria at the Magic Kingdom.  Paediatrics & Child Health 2008.  Volume 13 Issue 7: 615-618

M Salvadori, J M. Sontrop, AX.Garg, Jennifer Truong, Rita S. Suri, FH Mahmud,  J J. Macnab, WF. Clark.  Pediatric Hypertension in Relation to Obesity in a Rural Canadian Community. 2008. Pediatrics. Vol. 122 No. 4 October 2008, pp. e821-e827

Mahmud FH, D Ramsey, S Levin, R.N. Singh, T Kotylak, and DD Fraser. Coma with Diffuse White Matter Hemorrhages in Juvenile Diabetic Ketoacidosis. Pediatrics 2007 120:6 e1540-1546

Domené HM, Scaglia P, Lteif A, Mahmud FH, Kirmani S, Frystyk J, Bedecarrás P, Gutiérrez M, Jasper HG. Phenotype effects of complete and haplo ALS insufficiency in a family presenting two novel IGFALS gene mutations. Journal of Clinical Endocrinology & Metabolism 2007 92: 4444-4450

Haller  M.J., J Stein, J Schuster, D Therieaque, J Silverstein, DA Schatz, MG Earing, & FH Mahmud. Endo-PAT Demostrates Endothelial Function in Children with Type 1 Diabetes. Pediatric Diabetes 2007 8: 193-198.

Mahmud FH Micheal G. Earing, Robert A. Lee, Aida N. Lteif, David J. Driscoll & Amir Lerman . Altered Endothelial Function in Asymptomatic Male Adolescents with Type 1 Diabetes. Congenital Heart Disease 2006: 1, 98-103.

Mahmud, FH, Murray JA , Kudva Y, Zinsmeister AR, Dierkhising RA, Lahr BD, Dyck PJ, El-Youssef M, Burgart LJ, Van Dyke CT, Brogan DL & L. J Melton III . Celiac Disease in Type 1 Diabetes in a North American Community: Prevalence, Serology and Clinical Features. Mayo Clinic Proceedings. 2005 80 (11) : 1429-34.  
 
Mahmud, FH A Linglart, M Bastepe, H Juppner & A N Lteif.  Familial Pseudohypoparathyroidism type Ib Presenting as ‘Paroxysmal Dyskinesia’.2005 Pediatrics 115(2):e242-4.

Soares-Welch C, Farhy L, Mielke KL, Mahmud FH, Miles JM, Bowers CY, Veldhuis JD. Complementary Secretagogue Pairs Unmask Prominent Gender-Related Contrasts in Mechanisms of Growth-Hormone Pulse Renewal in Young Adults. 2005 Journal of  Clinical  Endocrinology & Metabolism. 2005;90 2225-2232

Kourennyi D.E., Liu X., Hart J., Mahmud FH, Baldridge W.H. & Barnes S. Reciprocal modulation of calcium dynamics at rod and cone photoreceptor synapses by nitric oxide. 2004. Journal of Neurophysiology; 92(1):477-83.     

Mahmud, FH, Lteif, A.N., Renaud D.L., Reed A.M. and Brands C.K. Steroid Responsive Encephalopathy Associated with Hashimoto's Thyroiditis in an Adolescent with Chronic Hallucinations and Depression: Case Report and Review. 2003. Pediatrics; 112: 686-690.  

Mahmud FH, Thomas, K.B. & Schwenk II, W.F.  Radiologic Features of Renal Osteodystrophy in a Patient with "Normal" Bone Mineralization. 2003, Journal of Pediatrics. 143, 279.  

Barnes S., Merchant V. & Mahmud F. Modulation of Transmission gain by protons at the photoreceptor output synapse. 1993. Proceedings of the National Academy of Sciences (USA). Vol. 90, 10081-10085.