About Sickkids
About SickKids

Farid Mahmud, M.D.

The Hospital for Sick Children

Research Institute
Associate Scientist
Physiology & Experimental Medicine

University of Toronto
Associate Professor

Phone: 416-813-6218
Fax: 416-813-6304
Alternate Contact: Lindsay Paterson
Alternate Phone: 416-813-6218
Alternate e-mail: lindsay.paterson@sickkidsca

For more information, visit:


Brief Biography

Farid Mahmud received his medical degree at The University of Alberta, Edmonton. He trained in Paediatric Endocrinology and Metabolism at The Mayo Clinic, Rochester.

He is currently Staff Physician in the Division of Endocrinology, Department of Paediatrics and Assistant Professor at the University of Toronto and Associate Scientist at The Hospital for Sick Children Research Institute.

Clinical Care Activities

Dr. Mahmud is involved in care with patients with endocrine disorders and diabetes.

Research Interests

Dr. Mahmud's overall research focus is diabetes, clinical and translational research, relating to co-morbid autoimmune conditions and early evaluation and prevention of related complications.  His research interests include:

1. Evaluation of Vascular Function and Early Atherosclerosis in Paediatric cohorts at high risk for Cardiovascular disease in adulthood.

2. Interventions in High Risk Paediatric groups including Type 1 and Type 2 Diabetes to alter CVD risk. As part of an international, double-blind, randomized control trial, Dr. Mahmud serves as Principal Investigator of the Adolescent Diabetes Cardio-Renal Intervention Trial (AdDIT) Expansion in Canada.

3. Assessment of Comorbid Autoimmune conditions: impact of Celiac Disease and Type 1 Diabetes. Dr. Mahmud has a longstanding interest in Celiac Disease as an association with Type 1 Diabetes. He serves as Principal Investigator of a dietary intervention study (Celiac Disease and Diabetes - Dietary Intervention and Evaluation Trial (CD-DIET).  


Mohammed J, Deda L, Clarson C, Cuerden M, Mahmud FH. Assessment of habitual physical activity in adolescents with type 1 diabetes. Canadian Journal of Diabetes 2014: 38 (4): pp 250-255.

Har RL, Reich HN, Scholey JW, Daneman D, Dunger Db, Moineddin R, Dalton RN, Motran L, Elia Y, Deda L, Ostrovsky M, Sochett EB, Mahmud FH, Cherney DZ. The urinary cytokine/chemokine signature of renal hyperfiltration in adolescents with type 1 diabetes. Public Library of Science (PLoS One) 2014: 9 (11): e111131.

Assor E, Davies-Shaw J, Marcon MA, Mahmud FH. Estimation of dietary gluten content using total protein in relation to gold standard testing in a variety of foods. Journal of Nutrition and Food Sciences 2014: 4 (5): doi. 1000296.

Deda L, Sochett EB, Mahmud FH. Physiological changes in blood pressure impact peripheral endothelial function during adolescence. Cardiology in the Young 2014: 16 (6): pp 1-3.

Clarson C, Brown H, De Jesus S, Jackman M, Mahmud FH, Prapavessis H, Robinson T, Shoemaker K, Watson M, Dowd J, Hill DJ. Effects of a comprehensive, intensive lifestyle intervention combined with Metformin extended release in obese adolescents. International Scholarly Research Notices 2014 (2014).

Lawson ML, Bradley B, McAssey K, Clarson C, Kirsch S, Mahmud FH, Curtis JR, Richardson C, Courtney J, Cooper T, Downie C (on behalf of the CGM TIME Trial Study Group and the JDRF Canadian Clinical Trial Network CCTN1101).  The JDRF CCTN CGM TIME Trial – Timing of Initiation of Continuous Glucose Monitoring in Established Pediatric Type 1 Diabetes: Study protocol, recruitment and baseline characteristics of enrolled subjects.  BMC Pediatrics 2014: 14: pp 183.

Evans K, Richardson C, Landry A, Muileboom J, Cormack C, Mahmud FH, Lawson ML (for the CGM TIME Trial Study Group and the JDRF Canadian Clinical Trial Network CCTN1101). Experience with the Enlite Sensor in a Multicentre Pediatric Study.   Diabetes Educator 2014.

Marcovecchio ML, Woodside J, Jones T, Daneman D, Neil A, Prevost T, Dalton RN, Deanfield J, Dunger DB, Acerini C, Ackland F, Anand B, Barrett T, Birrell V, Campbell F, Cheetham T, Cooper C, Doughty I, Dutta A, Edge J, Hamilton-Shield J, Heywood J, Leech N, Mann N, Parker R, Rayman G, Robinson JM, Russell-Taylor M, Sankar V, Thalange N, Wilson M, Bergman P, Rodda C, Cameron F, Cotterill A, Couper J, Davis E, Donaghue K, Craig M, King B, Verge C, Mahmud FH, Clarson C, Curtis J, Sochett E, AdDIT Investigators . Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): urinary screening and baseline biochemical and cardiovascular assessments. Diabetes Care 2014: 3 (37): pp 805-813.

Oren A, Wang MK, Brnjac L, Mahmud FH, Palmert MR. Mild neonatal hyperthyrotropinaemia: 10 year experience suggests the condition is increasingly common but often transient. Clinical Endocrinology (Oxford) 2013: 79 (6): pp 832-837.

Cherney DZ, Reich HN, Scholey JW, Daneman D, Mahmud FH, Har RL, Sochett EB. The effect of aliskiren on urinary cytokine/chemokine responses to clamped hyperglycaemia in type 1 diabetes. Diabetologia 2013: 56 (10): pp 2308-2317.

Hill DJ, Prapavessis H, Shoemaker JK, Jackman M, Mahmud FH, Clarson C. Relationship between birth weight and metabolic status in obese adolescents. ISRN Obesity 2013: 2013 (2013): Article ID 490923.

Har R, Scholey JW, Daneman D, Mahmud FH, Dekker R, Lai V, Elia Y, Fritzler ML, Sochett EB, Reich HN, Cherney DZ. The effect of renal hyperfiltration on urinary inflammatory cytokines/chemokines in patients with uncomplicated type 1 diabetes mellitus. Diabetologia 2013: 58 (5): pp 1166-1173.

Zuijdwijk C, Cuerden M, Mahmud FH. Social determinants of health in pediatric type 1 diabetes. Journal of Pediatrics 2013: 162 (4): pp 730-735.