Workshop Agenda

Neonatal Infectious Diseases in Developing Countries
May 3, 2006
Hilton San Francisco, U.S.A.

8 – 10 a.m.
First Plenary Session
Plaza A (Lobby Level, Bldg 2)

Introduction

Alvin Zipursky, The Programme for Global Paediatric ResearchTM, Toronto, Canada

Neonatal infectious diseases in low- and mid-income countries: The need for research
Dr. José Santos Preciado, Director General, Hospital Infantil de México Federico Gómez, Mexico City, Mexico

The development and use of modern diagnostic technology in low- and mid-income settings
Samir Saha, Professor, Dept. of Microbiology, Dhaka Shishu (Children) Hospital
Bangladesh Institute of Child Health, Dhaka, Bangladesh

The pharmacology of antibiotic therapy and drug resistance
John Van Den Anker Chief, Division of Pediatric Clinical Pharmacology, Children’s National Medical Center, Washington, D.C. U.S.A.

Introduction to Small Group Sessions

Alvin Zipursky will provide directions for the small group studies: All groups will be asked to develop recommendations of important research needs surrounding the problem of neonatal infections in mid- and low-income countries. This should include discussion about the role PGPR can best play in helping advocate for and implement those research recommendations.

10 – 10:30 a.m.
Coffee Break*

10:30 a.m. – 2p.m.**
Small Group Sessions

Group 1

Location: Union Square 19 (Bldg 3, Level 4)
Chairs: Stuart MacLeod, British Columbia Research Institute for Children’s and Women’s Health, Vancouver, Canada; and Bo Sun, Children’s Hospital of Fudan University, Shanghai, China
Topic: Antibiotic therapy and drug resistance in the treatment of neonatal infections in mid- and low-income countries
Questions to be discussed:
a. What research is needed to determine the appropriate use of antibiotics and the prevention of practices that lead to drug resistance in mid- and low-income countries?
b. What research is needed on problems related to accessibility and availability of drugs in mid- and low-income countries?

Group 2

Location: Union Square 20 (Bldg 3, Level 4)
Chairs: Zulfiqar Bhutta, The Aga Khan University, Karachi, Pakistan; and Jack Sinclair, Cochrane Neonatal Review Group, Hamilton, Canada
Topic: Diagnosis and treatment of neonatal infections in rural communities in mid- and low-income countries
Questions to be discussed:
a. What research is needed concerning the diagnosis of neonatal infection, both in hospital and community settings?
b. What research is needed on therapy, both in hospital and community settings, and what are the benefits and risks associated with such therapy?
c. Are there research needs surrounding long-term morbidity from infection?

Group 3

Location: Union Square 21 (Bldg 3, Level 4)
Chairs: Philip Fischer, Mayo Clinic, Rochester, U.S.A. and Demissie Habte, BRAC University, Dhaka, Bangladesh
Topic: Development of research infrastructure for the study of neonatal infections in mid- and low-income countries
Questions to be discussed:
a. What research will help determine the need for and feasibility of establishing diagnostic facilities in mid- and low-income countries?
b. What research issues surround training of personnel who will remain on site?
c. What research issues surround the issue of linkage to international research programs as a means of sustaining quality and collaboration?

Group 4

Location: Union Square 25 (Bldg 3, Level 4)
Chairs: Gary Darmstadt, Johns Hopkins University, Baltimore, U.S.A.; and Margaret Nakakeeto, Mulago Hospital, Kampala, Uganda
Topic: Prevention of nosocomial and environmentally caused infections in mid- and low-income countries
Questions to be discussed:
a. What research is necessary to lead to a reduction of nosocomial and environmentally-caused infections in mid- and low-income countries? This query includes the following sub-query:
b. What research will help further determine the importance of the skin in resisting the development of nosocomial and environmentally-related infections?
c. What research will help further determine the importance of and best practices in umbilical cord management, vaginal antisepsis, breast feeding, and handwashing as ways of preventing nosocomial infections? 

2 – 2:30 p.m.
Coffee Break*

2:30 – 5 p.m.
Second Plenary Session

Plaza A (Lobby Level, Bldg 2)

-         Presentations from each of the small groups, summarizing discussions and recommendations
-         General discussion and preparation of final recommendations