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Paediatric Laboratory Medicine

Herpes group I PCR (HSV-1, HSV-2, VZV)

Test Name

Herpes group I PCR (HSV-1, HSV-2, VZV)

Alternate Name/ Synonym

Herpes simplex virus-1, herpes simplex virus-2, varicella zoster virus

Gene Name

Proprietary

Test Code

HHVPC, HVOPC, HVOPCC, HVOPCP

Division

Molecular Microbiology - Viral

Method

Real-time Polymerase Chain Reaction

External Proficiency Testing

College of American Pathologists

Turn Around Time

Within 4 days

Disease/Condition

HSV-1 and HSV-2:

  • Herpes labialis
  • Herpes genitalis
  • Gingivostomatitis
  • Herpetic whitlow
  • Eczema herpeticum
  • Cold sore
  • Encephalitis
  • Meningitis                                       

VZV:

  • Chicken pox
  • Herpes zoster
  • Encephalitis

Specimen Type

  • CSF
  • Other sterile body fluids
  • Whole blood
  • Lesion scraping

Minimum Specimen Requirements

  • CSF 300 uL per 1 test, for multiple tests please ensure adequate sample volume is submitted
  • Sterile screw top container for other sterile body fluids
  • Whole blood (EDTA) - 1 mL minimum for 1 test, 3-5 mL recommended for multiple tests
  • Lesion scraping in universal transport medium       

Storage/Transportation

  • All specimens must be shipped on dry ice
  • Exception: Specimens that will arrive at SickKids within 24 hours from the time of collection can be shipped on ice packs

Special Requirements

* Not Health Canada approved

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212