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Paediatric Laboratory Medicine

Ghrelin

Background

* For research purposes only

Clinical Significance

Metabolic syndrome is a cluster of conditions that occur together, including increased blood pressure, elevated insulin levels, excess body fat around the waist and abnormal cholesterol levels. Key features of metabolic syndrome include insulin resistance, glucose intolerance, hypertension, dislipidemia and central obesity - all of which are risk factors for artherosclerosis, coronary heart disease, type 2 diabetes, kidney disease and even premature death. Several gut hormones or peptide hormones have been identified and play a significant role in the regulation of gut motility and secretion, pancreatic islet hormone secretion, food intake, energy expenditure and taking part in both neurotransmission and neuromodulation.

Test Name

Ghrelin

Test Code

RD037

Division

Biochemistry- Test Development Multiplex

Method

Luminex Multiplex

Turn Around Time

Batch testing (37 samples)

Disease/Condition

Diabetes and obesity

Specimen Type

Serum or EDTA Plasma

Minimum Specimen Requirements

300 uL for the whole cytokine panel

Storage/Transportation

Store samples at -20°C. Avoid multiple (>2) freeze thaw cycles. All samples must be stored in polypropylene tubes. Do not store samples in glass. Avoid using samples with gross hemolysis or lipemia.

Special Requirements

Add serine protease inhibitor to blood (for active ghrelin measurement).

Approval is required

CPT Codes

83520

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212