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Paediatric Laboratory Medicine

C-Peptide

Clinical Significance

Measurements of C-peptide more accurately reflect pancreatic insulin secretion rates than insulin. C-peptide is used as a test of β-cell function in human subjects in a variety of conditions including type 1 diabetes, and to aid in the differential diagnosis of hypoglycemia, and surreptitious insulin self-administration.6,7,8 A low C-peptide level is expected if the insulin secretion is diminished as in insulin-dependent diabetes (type 1 diabetes, latent autoimmune diabetes of adults (LADA)). Elevated C-peptide levels may be found when β-cell activity is increased as in hyperinsulinism and insulinomas. Elevated C-peptide levels may be found when β-cell activity is increased as in hyperinsulinism and insulinomas.

Test Name

C-Peptide

Test Code

RD035

Division

Biochemistry- Test Development Multiplex

Method

Automated Immunoassay Analyzer

Turn Around Time

Batch testing (50 samples)

Disease/Condition

Diabetes & obesity

Specimen Type

Serum

Minimum Specimen Requirements

200 uL

Storage/Transportation

Send frozen

Special Requirements

* For research purposes only.

Approval is required

CPT Codes

86141

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Reference Range

298 - 2350 pmol/L