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Paediatric Laboratory Medicine

11-Deoxycortisol, Blood

Clinical Significance

11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.

Test Name

11-Deoxycortisol, Blood

Test Code

SP11DC

Division

Biochemistry - Biochemistry

Method

LC-MS/MS

External Proficiency Testing

CAP, SKML (Foundation for Quality Assessment in Medical Laboratories)

Turn Around Time

Tuesday & Thursday

Specimen Type

Serum or Plasma 

Minimum Specimen Requirements

500 uL

Storage/Transportation

Frozen

Approval is not required

CPT Codes

82634

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Reference Range

Age

Range (nmol/L)

0 – <1y

0.0 – 5.3 

1 – <2y

0.1 – 0.9

2 – <7y

0.1 – 1.1

7 – <19y

0.1 – 2.3

Adult

See attachment