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Paediatric Laboratory Medicine

Corticosterone, Blood

Clinical Significance

Measurement of corticosterone may help confirm the diagnosis of the very rare aldosterone deficiency disorder, corticosterone methyl oxidase (18-hydroxylase) enzyme deficiency where the ratio of corticosterone to 18-hydroxycosticosterone may be increased.

Test Name

Corticosterone, Blood

Test Code

SPCOCO

Division

Biochemistry - Biochemistry

Method

LC-MS/MS

External Proficiency Testing

KKGT - Netherlands (Association for Quality Assessment in Therapeutic Drug Monitoring and Clinical Toxicology)

Turn Around Time

Tuesday & Thursday

Specimen Type

Serum, Plasma

Minimum Specimen Requirements

400 uL

Approval is not required

CPT Codes

82528

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Reference Range

Age

Range (nmol/L)

0 – <1m

0.1 – 20.0 

1m – <1y

0.3 – 15.4

1 – <4y

0.6 – 3.7

4 – <6y

1.0 – 4.1

6 – <15y

 0.4 – 9.2

15 – <19y

0.9 – 15.2

Adult

See attachment