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Paediatric Laboratory Medicine

FISH - X/Y - Peripheral Blood

Clinical Significance

Monitoring of proportion of donor cells to recipient cells in an uncultured sample of peripheral blood, when there is an opposite sex donor

Test Name

FISH - X/Y - Peripheral Blood

Gene Name

Centromeres X and Y

Division

Cytogenetics

Method

Uncultured blood, direct harvest; FISH (Fluorescence in situ hybridization)

External Proficiency Testing

CAP
QMPLS

Disease/Condition

Bone marrow transplant monitor

Specimen Type

Peripheral blood

Minimum Specimen Requirements

Blood at room temperature in sodium heparin
Volume: 0-3 months  1-3 mL
                3 months-12 years: 3-6 mL
                12 years - adult: 6 mL

Storage/Transportation

Maintain at room temperature. Do not refrigerate or freeze.

Special Requirements

Collect in sodium heparin tube

Shipping and Contact Information

The Hospital for Sick Children
Rapid Response Laboratory
170 Elizabeth Street, Room 3642
Toronto, ON
M5G 2G3
Canada
Phone: 416-813-7200
Phone: 1-855-381-3212

Interpretation

Provided