Haemoglobin A1C

Alternate test name

Glycosylated / Glycated Haemoglobin

Lab area

Clinical Biochemistry - General

Method and equipment

Equipment : Roche Cobas Pro c503

Method : The HbA1c determination is based on the turbidimetric inhibition immunoassay (TINIA) for hemolyzed whole blood.

This method uses TTAB* as the detergent in the hemolyzing reagent to eliminate interference from leukocytes (TTAB does not lyse leukocytes).
Sample pretreatment to remove labile HbA1c is not necessary. All hemoglobin variants which are glycated at the β‑chain N‑terminus and which have antibody-recognizable regions identical to that of HbA1c are determined by this assay. Consequently, the metabolic state of patients having uremia or the most frequent hemoglobinopathies (HbAS, HbAC, HbAE, HbAD) can be determined using this assay

Expected turn-around time

STAT/Urgent/Routine: 3 days

Shipping information

Background and clinical significance

HbA1c determinations are useful for monitoring of long‑term blood glucose control in individuals with diabetes mellitus. This test is also to be used as an aid in diagnosis of diabetes and identifying patients who may be at risk for developing diabetes.