Research Institute Core Facilities & Resources
There are over a dozen scientific core facilities at the SickKids Research Institute (RI). These core facilities provide researchers across the research community, internal and external to SickKids, access to specialized technical platforms, scientific expertise, and highly skilled personnel to enhance the scope and quality of their health research.
Operated on a cost recovery model, these facilities offer state-of-the-art instrumentation, consultation, and research design services that are typically too specialized or costly for individual laboratories to maintain.
World-class facilities for your research
Enhance the scope and quality of your research. Conduct your studies in a world-class setting equipped with new technologies and infrastructure – check out our facilities below and learn what our distinct research design services can offer you.
Take a tour
Analytical Facility for Bioactive Molecules (AFBM)
The Analytical Facility for Bioactive Molecules (AFBM) offers a range of services for researchers interested in quantitative and qualitative analysis of biological samples. Services include the analysis of drugs, metabolites, lipids, amino acids, and other small molecules by chromatography and mass spectrometry (LC-MS/MS, GC-MS, IR-MS, GC and HPLC).
SickKids-UHN Flow and Mass Cytometry Facility (FMCF)
The Flow and Mass Cytometry Facility (FMCF) provides academic and corporate clients access to several state-of-the-art analytical flow cytometers and high-speed cell sorting services. FMCF also offers comprehensive training and education, as well as expert consultation services, to help users leverage our technology to elevate their research.
The Centre for Computational Medicine (CCM)
The Center for Computational Medicine (CCM) provides scientists and clinicians at SickKids with computational expertise, including High Performance Computing resources, Bioinformatics Analysis consulting and software development. The CCM also works with biological/medical and computational scientists at SickKids to identify appropriate collaborators.
The Centre for Phenogenomics (TCP)
The Centre for Phenogenomics (TCP) is a centralized, state-of-the-art national research facility. TCP’s animal resources, model production, clinical phenotyping, infection and inflammation, imaging, pathology, and cryopreservation and recovery services are available to researchers worldwide.
Research equipment database
The Research Institute’s Equipment Database gives researchers access to over 3000 pieces of top-level research equipment used across SickKids’ labs and programs. Resource and knowledge sharing fosters collaboration amongst our research community, helping researchers view and advance projects from every perspective.
Navigating the database
- Search equipment by keywords. (i.e. cell counter, microscope, cryostat, etc.)
- Filter by floor or program
- Important: Always request permission from the primary contact through email first
- For a comprehensive search result (e.g. full equipment by floor, PI, lab, etc.), please contact Nancy Silva-Gagliardi or Craig Urekar.
SickKids research databases
Access some of the largest and most comprehensive databases used by research communities at SickKids and around the globe to further the quality and scope of their health research.
The Database of Genomic Variants (DGV) provides a comprehensive summary of structural variations in the human genome. The database only represents structural variation identified in healthy control samples. The DGV’s useful catalog of control data is used in studies aiming to correlate genomic variation with phenotypic data. The database is continuously updated with new data from peer reviewed research studies, and is maintained by The Centre for Applied Genomics at SickKids.
Documents mutations in the CFTR gene, and doubles as a resource for the international cystic fibrosis genetics research community.
A repository of DNA samples for future research aimed at identifying the genes that cause congenital heart disease, and to develop better ways to diagnose, prevent and treat heart disease in children and adults.
Along with the shRNA archive, these are two of the different database resources provided by the SickKids Proteomics, Analytics, Robotics & Chemical Biology Centre (SPARC).
Four hospitals, one goal. This central virtual registry facilitates postings and annotations of available samples from all CNS tumour cases across four Toronto University Hospitals: SickKids, St. Michael's, Sunnybrook Health Sciences Centre, and UHN.
Meet our Researchers
Meet the scientists and clinicians working at SickKids.
SickKids actively promotes a culture of research integrity, providing integrity education and resources to staff and collaborators.
Clinical Research Services
Clinical Research Services supports study teams and quality clinical research by providing tools, templates, education, facilities and more.