SickKids Research Institute
Driving clinical impact with every
SickKids Research Institute (RI) is where over 2,000 researchers, trainees, and staff are working together to take on the toughest challenges in child health. As Canada’s largest, hospital-based child health research institute, we conduct and translate groundbreaking research to improve child health outcomes, policy, and clinical care, train the next generation of researchers, and support global scientific communities with knowledge and state-of-the-art facilities.
Innovation and collaboration across our seven distinct research programs have led to a number of incredible discoveries at SickKids, uncovering the mechanisms and outcomes of childhood disease. And with every research question in the lab, we are driving clinical changes.
By challenging existing care models and maximizing research translation, we’re taking more discoveries from the lab bench to the bedside, making a bigger impact on children’s lives around the world, sooner.
By the numbers
1,018 research trainees
394 project & team investigators
1,126 research support staff
$262.6M research spend
#1 research intensity among Canadian hospitals
#2 among Canada's top research hospitals in total research spending
Explore the Institute
As one of Canada's top research hospitals, families that walk through our doors have a chance to participate in clinical research to help address our greatest health challenges.
Latest research news
December 5, 2022
New SickKids research identifies key immune and microbial factors in the gut that influence newborn stem cell development, with implications for the treatment of necrotizing enterocolitis.
November 28, 2022
SickKids researchers develop an innovative computational method called RNAmp to measure hypertranscription in human tumours, with novel implications for cancer care.
November 24, 2022
The Structural & Biophysical Core Facility is a centralized hub of state-of-the-art research instruments and expertise where scientists collaborate to advance paediatric medicine.
Cutting-edge methods in cell and molecular biology, biochemistry, and microscopy allow us to understand how cells function, and how these functions go awry in disease states.
Child Health Evaluative Sciences
By conducting and translating research into clinical practice, system, and policy, this research aims to improve the health and well-being of children and their families.
Developmental & Stem Cell Biology
Using development genetics, genomics, and stem cell biology, these research teams are developing new therapeutic approaches for children and youth.
More from the Research Institute
Canada Research Chairs showcase the calibre and diversity of scientists and clinicians working at the SickKids Research Institute.
SickKids is home to 48 scientific and academic chairs. See who holds current chairs in Canada.
Led by internationally-recognized leaders in research, the SickKids Scientific Advisory Board (SAB) guides the strategic direction for the RI, establishes and monitors KPIs, and leads external reviews of the seven SickKids research programs.
- Director and Professor of Child Health, UCL Great Ormond St Institute of Child Health
Rosalind Smyth is Director of the UCL Great Ormond Street Institute of Child Health, Honorary Consultant Respiratory Paediatrician at Great Ormond Street Hospital and Non-Executive Director of Great Ormond Street Hospital NHS Foundation Trust.
Her current research interest include clinical studies of viral/host interactions in RSV bronchiolitis, clinical trials and systematic reviews of treatments for childhood respiratory disease. Smyth previously served as Professor of Paediatric Medicine at The University of Liverpool UK and held the position of Director of the UK Medicines for Children Research Network, which supports a variety of paediatric research with children across all of England.
The Research Institute is currently seeking new members for the Scientific Advisory Board.
Contact the Research Institute
For all inquiries about SickKids Research Institute, please contact Jelena Djurkic, Manager, Communications (Research Institute & Strategic Initiatives), Communications & Public Affairs