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Fluorescence in situ Hybridization (FISH) - Tissue
Alternate test name
FISH
o Wolf-Hirschhorn (4p16)
o Williams (7q11.23)
o Prader-Willi/Angelman (15q11.2)
o Smith-Magenis (17p11.2)
o Microdeletion 22q11.2
o X/SRY
o SHOX (Xp22.3/Yp11.3)
o Microarray Follow Up FISH
o Other
Lab area
Genome Diagnostics - Cytogenetics
Method and equipment
Cell culture; FISH (Fluorescence in situ hybridization)
Expected turn-around time
4 weeks
Specimen type
Tissue
Specimen requirements
Minimum 2-3 mm3 fresh tissue (skin biopsy)
Storage and transportation
Refrigerate until time of shipment. Ship sample overnight at room temperature for receipt at SickKids Cytogenetics Laboratory within 24 hours of collection.
Special requirements
Place in sterile container with SickKids Cytogenetics transport media or other sterile culture media
Shipping information
The Hospital for Sick Children
Division of Genome Diagnostics
555 University Avenue, Black Wing, Room 3416
Toronto, ON
Canada
M5G 1X8
Phone: 416-813-7200 ext. 2
Hours: Monday to Friday, 8 a.m. to 4:30 p.m.
Off hours: Please send to Rapid Response Laboratory, 555 University Avenue, Room 3642
Email Molecular Lab: molecular.lab@sickkids.ca
Email Cytogenetics: cytogenetics.requests@sickkids.ca
Background and clinical significance
Disease condition
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Customer Service
Toll Free: 1-855-381-3212
Local: 416-813-7200