Paul Nathan

Head of Solid Tumour Section
Director, Aftercare Program
Division of Haematology/Oncology

Senior Associate Scientist
Child Health Evaluative Sciences

Dr. Paul Nathan is Director of the Aftercare clinic and the Section Head of the Solid Tumor section in the Division of Paediatric Hematology/Oncology and a Senior Associate Scientist in the Research Institute at The Hospital for Sick Children. He is a Professor of Paediatrics and Health Policy, Management and Evaluation at the University of Toronto. His research is focused on health care utilization by adult survivors of childhood cancer, as well as specific “late effects” of cancer therapy, including cardiac disease and second malignant neoplasms. He is a member of several North American research and clinical committees focused on research, clinical care, and policy creation for long-term survivors of childhood cancer.

Research

Dr. Nathan’s clinical practice and research program is focused on survivors of childhood cancer. His research addresses specific "late effects" of cancer therapy (such as cardiac disease) as well as healthcare utilization and screening for complications in survivors. He is a member of the steering committees of the Children’s Oncology Group (COG) Survivorship and Outcomes Committee, and the Childhood Cancer Survivor Study (CCSS). Dr. Nathan and his colleagues at SickKids have established a research unit in the SickKids Research Institute, Real-world Outcomes of Cancer in Children and Adolescents (ROCCA). ROCCA’s mission is to leverage Ontario and Canada’s unique administrative data to evaluate real-world health and socioeconomic outcomes across the paediatric and adolescent/young adult (AYA) cancer journey.

Education and experience

• 2003–2004: Fellowship, Advanced Studies Program in Pediatric Oncology, National Cancer Institute, Pediatric Oncology Branch, Bethesda, Maryland
• 2001–2003: M.Sc., Clinical Health Sciences, Health Research Methodology, McMaster University, Hamilton, Ontario
• 2001–2003: Clinical Research Fellow, Paediatric Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario
• 1999–2001: Fellow (Chief Fellow: 2000-01), Paediatric Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario
• 1995–1999: Resident (Chief Resident: 1998-99), Paediatrics, The Hospital for Sick Children, Toronto, Ontario
• 1991–1995: MD, University of Toronto, Toronto, Ontario

Achievements

• 2024: Research Impact Award, Department of Pediatrics, The Hospital for Sick Children. Recognizes a physician within 10-20 years of appointment to an academic health sciences centre, who has generated a body of research that is exerting a major impact in a field of study.
• 2023: Visionary Award, Paediatric Oncology Group of Ontario
• 2014: Manuscript Award Best Oncology Paper of 2013 (Research Award), Gudas Award - American Physiotherapy Association
  Manuscript, “A Comprehensive Healthy Lifestyle Program for Children Receiving Treatment for Acute Lymphoblastic Leukemia: Feasibility and Preliminary Efficacy Data”
• 2010: Manuscript Award, American Society of Clinical Oncology (ASCO) (Research Award)
  Manuscript, “Cancer Screening in Adult Survivors of Childhood Cancer” chosen as one of the major research advances in cancer treatment, prevention and screening in 2009
• 2008: Manuscript Award, American Society of Clinical Oncology (ASCO) (Research Award)
  Manuscript, “Risk Based Care in Survivors of Childhood Cancer” chosen as one of the major research advances in cancer treatment, prevention and screening in 2007

1. Fournier E, Joye R, Pozza A, Hui W, Friedberg MK, Lam E, Runeckles K, Signorile M, Fan S, McCrindle B, Mertens L, Nathan PC. Vascular Health and Early Atherosclerosis in Childhood Cancer Survivors: Reassuring Findings From Comprehensive Noninvasive Assessment. JACC Adv. 2025 Nov 26;5(1):102349. doi: 10.1016/j.jacadv.2025.102349. Epub ahead of print. Impact Factor: 22.3.
2. Nathan PC, Lau C, Ng VL, Miserachs M, Teoh CW, Solomon M, Dipchand AI, Locke M, Gupta S. Outcomes after solid organ transplantation in survivors of childhood, adolescent, and young adult cancer: a population-based study. J Natl Cancer Inst. 2025 Sep 1;117(9):1809-1816. doi: 10.1093/jnci/djaf106. Impact Factor: 10.0.
3. Shuldiner J, Sutradhar R, Lau C, Shah N, Lam E, Ivers N, Nathan PC. Longitudinal adherence to surveillance for late effects of cancer treatment: a population-based study of adult survivors of childhood cancer. CMAJ. 2024 Mar 10;196(9):E282-E294. doi: 10.1503/cmaj.231358. PMID: 38467416; PMCID: PMC10927290. Impact Factor: 12.3.
4. Nathan PC, Huang IC, Chen Y, Henderson TO, Park ER, Kirchhoff AC, Robison LL, Krull K, Leisenring W, Armstrong GT, Conti RM, Yasui Y, Yabroff KR. Financial Hardship in Adult Survivors of Childhood Cancer in the Era After Implementation of the Affordable Care Act: A Report From the Childhood Cancer Survivor Study. Journal of Clinic Oncology. 2023 Feb 10;41(5):1000-1010. Impact factor 44.54
5. Zgardau A, Ray JG, Baxter NN, Nagamuthu C, Park AL, Gupta S, Nathan PC. Obstetrical and perinatal outcomes in female survivors of childhood and adolescent cancer: A population-based cohort study. Journal of the National Cancer Institute. Apr 2022;114(4):553-564. Impact factor 13.51
6. Cullinan N, Schiller I, Di Giuseppe G, Mamun M, Reichman L, Cacciotti C, Wheaton L, Caswell K, Di Monte B, Gibson P, Johnston DL, Fleming A, Pole JD, Malkin D, Foulkes WD, Dendukuri N, Goudie C, Nathan PC. Utility of a Cancer Predisposition Tool for Predicting Subsequent Malignant Neoplasms in Childhood Cancer Survivors. Journal of Clinical Oncology. Oct 2021;39(29):3207-3216. Impact factor 44.54

View a full list of Paul Nathan's publications