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SickKids researchers show whole genome sequencing should be standard diagnostic test for children with medical complexity

November 12, 2020

A new study from researchers and clinicians at SickKids shows whole genome sequencing could provide the diagnostic answers families are seeking and open up new avenues for treatment in a shorter period of time.

Dr. Gregory Costain

Dr. Upton Allen from SickKids leads team assessing COVID-19 prevalence, risk factors among Black Canadian communities

September 15, 2020

Medical researchers from SickKids are conducting largescale antibody testing and data collection to understand the prevalence of COVID-19 infection in Black Canadian communities.

Photo of Dr. Upton Allen

SickKids study finds increased risk of leukemia relapse for children who miss doses of certain cancer therapy

April 13, 2020

A research team is investigating whether missing a dose or multiple doses of a type of therapy increased risk of relapse in children with acute lymphoblastic leukemia.

Pipette in a research lab

SickKids researchers studying plasma of COVID-19 survivors

May 29, 2020

SickKids is helping lead a cross-country effort to better understand and create a therapy to treat COVID-19 with convalescent plasma.

Plasma stand next to boy with boxing gloves on his hands

New tool to help doctors better prevent sudden cardiac death in children

May 20, 2020

A research team from SickKids has proven that a digital tool they developed can successfully identify paediatric patients with cardiomyopathy who are at high risk for sudden cardiac death.

Close up photo of gloved hands and scrubs

Researchers and teachers provide initial observations from school simulation study

September 14, 2020

SickKids researchers and teachers involved in a COVID-19 safe schools simulation study have compiled preliminary observations and key learnings from their experience.

SickKids-led research team discovers mechanism that leads leukemia cells to trigger bone loss, identifies a potential therapy to prevent it in lab models

September 21, 2020

Researchers have discovered a process that may trigger bone loss in patients with childhood B-ALL, and identified an antibody that helped to prevent it in the lab.

This is a picture of a researcher in the lab.

SickKids researchers identify rare genetic variants linked to immune system regulation

March 29, 2021

New research co-led by SickKids identifies genetic variant associated with rare cases of hard-to-treat immune dysregulation and inflammation.

A man and woman hold a baby together on their laps.

Evidence grows for iron deficiency screening in childhood

January 7, 2020

One study details the known association between iron levels and cognitive function, and identifies a new threshold in blood tests that could guide more effective clinical intervention. The other is the first health-economic analysis of potential …

Photo of Sarah Carsley and Patricia Parkin at SickKids

Huntington’s disease-causing DNA repeat mutations reversed in the lab

February 27, 2020

Scientists reveal the ability to reverse repeat mutation length in the brains of a mouse model with Huntington’s disease. The team discovered a compound that targets the unusual DNA structure and was shown to reverse repeat expansions with …

Christopher Pearson hold up a DNA scan in the lab

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