Skip to Main Content Go to Sitemap

Anti-Liver Kidney Microsomal Antibody

Alternate test name


Lab area
Clinical Biochemistry - Immunology
Method and equipment

Indirect immunofluorescence (IFA), HEp-2 cell substrate 

Expected turn-around time
7 days
Specimen type


Specimen requirements

Send 0.3 mL for 1 test or 0.6 mL min for several tests from:

  • ANA, HEp-2 IgG
  • ANCA, IgG
  • EMA, IgA
  • GBM, IgG
  • LKM, IgG
  • PCA, IgG
  • SMA, IgG
  • dsDNA, IgG (Cithidia luciliae)
Storage and transportation


Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance

An anti-LKM antibody (anti–liver-kidney microsomal antibody or LKM antibody) is any of several autoantibodies that are detected in the serum of patients with different types of acute or chronic liver disease. These antibodies are targeted against antigens of the cytochrome P450 system.  ALKM are also used in the diagnosis of autoimmune hepatitis.

Back to Top