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Anti-Smooth Muscle Antibody

Alternate test name

ASMA, anti-SMA,

Lab area
Clinical Biochemistry - Immunology
Method and equipment

Indirect immunofluorescence (IFA), HEp-2 cell substrate 

Expected turn-around time
7 days
Specimen type


Specimen requirements

Send 0.3 mL for 1 test or 0.6 mL min for several tests from:

  • ANA, HEp-2 IgG
  • ANCA, IgG
  • EMA, IgA
  • GBM, IgG
  • LKM, IgG
  • PCA, IgG
  • SMA, IgG
  • dsDNA, IgG (Cithidia luciliae)
Storage and transportation


Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance

IgA anti-human tissue transglutaminase (h-tTG) antibodies in human serum. The presence of IgA anti-h-tTG antibodies, in conjunction with clinical findings and other laboratory tests, can aid in the diagnosis of the gluten sensitive enteropathies celiac disease (CD) and dermatitis herpetiformis (DH).

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