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Total Renin

Alternate test name

Direct Renin

Lab area
Clinical Biochemistry - General
Method and equipment

Method: CLIA (chemiluminescence)

Equipment: Diasorin Liaison XL

Expected turn-around time
7 Days
Specimen type

EDTA plasma

Specimen requirements

1.0 mL

Storage and transportation
  • Store and transport frozen.
Special requirements
  • Centrifuged and separated within 30 minutes of collection.
  • Immediately separate and freeze.
Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance

Renin is a proteolytic enzyme synthesized by the juxtaglomerular cells of the kidney. Renin plays an integral role in the Renin-Angiotensin-Aldosterone System. This system regulates blood pressure through blood volume, sodium and water homeostasis control and vasoconstriction.

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