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Mucopolysaccharides-TLC, urine
Alternate test name
Glycosamine-Glycuronoglycans, urine (GAGS)
Lab area
Clinical Biochemistry - Metabolic Diseases
Method and equipment
Identification of excess dermatan sulfate, heparan sulfate and keratan sulfate in urine by thin layer chromatography (TLC).
Expected turn-around time
30 days
Specimen type
Random Urine
Specimen requirements
15 mL of urine in sterile screw top container.
Storage and transportation
- Store at 4oC. Keep cool during transport.
Special requirements
MPS TLC is only performed if MPS screen is positive or if Morquio Syndrome suspected (Please specify).
Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
Canada
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Requisition
Background and clinical significance
Qualitative assessment
Disease condition
- Hurler Syndrome (MPS Ih)
- Hurler-Sheie Syndrome (MPS Ih/s)
- Sheie Syndrome (MPS Is)
- Hunter Syndrome (MPS II)
- Sanfilippo Syndrome (MP SIII)
- Morquio Syndrome (MPS IV)
- Maroteaux-Lamy Syndrome (MPS VI)
- Sly Syndrome (MPS VII)
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Customer Service
Toll Free: 1-855-381-3212
Local: 416-813-7200