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Tobramycin, plasma or serum

Lab area
Clinical Biochemistry - TDM & Toxicology
Method and equipment
Vitros 5600
Expected turn-around time
Stat: 1 hour Urgent/ Routine: 2 hours
Specimen type

Serum, Plasma (Heparin)

Specimen requirements

150 uL

Storage and transportation

4°C (transport with a cool pack if possible)

Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Background and clinical significance
Tobramycin is one of the aminoglycoside class of bactericidal drugs, also including streptomycin, neomycin, netilmycin, sisomycin, gentamicin, kanamycin, and amikacin. Due to toxic effects associated with aminoglycosides manifest as delayed-onset vestibular and cochlear sensory cell destruction and acute renal tubular necrosis, the goal of monitoring is to maintain therapeutic plasma concentration at minimum risk to patients.
Disease condition


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