Amikacin, plasma or serum
Serum, Plasma (Heparin or Citrate)
4°C (transport with a cool pack if possible)
Amikacin is indicated in the short term treatment of serious gram negative infections (Pseudomonas, Escherichia coli). It is particularly useful with those strains resistant to most other aminoglycosides of choice when gentamicin resistance is suspected.
As with other aminoglycosides, there is a narrow margin between therapeutic effectiveness and toxicity. Amikacin should be used with caution in patients with impaired renal function.
Toxic side effects may include: ototoxicity (hearing loss), neuromuscular blockage (muscle paralysis) and nephrotoxicity.
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