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High-quality stem cells enable researchers to better study almost any disease

December 5, 2019

Using whole genome sequencing, a collaborative team at SickKids and the University of Toronto has created high-calibre control induced pluripotent stem cells that can be used to study a variety of diseases.

Scientist looking into a microscope

Could on-and-off fasting help prevent obesity?

October 17, 2017

Researchers examined the effect of an intermittent-fasting regimen, without restricting caloric intake, in mice. They found that an 'on-and-off' fasting regimen not only prevented obesity in mice, but also improved metabolism by changing the quality …

Two men stand side by side in a lab wearing lab coats.

PICH2GO helps tackle children’s pain through art and discussion

November 15, 2016

For International Pain Awareness Week, the SickKids Pain Centre organized a series of educational and networking events, which brought together clinicians, researchers, trainees, patient families and policymakers to help engage, empower and educate …

A wall of framed drawings and paintings, depicting various scenes and subjects

New guidelines aim to reduce vaccination pain in children and adults

August 24, 2015

A new Canadian guideline, published online in CMAJ (Canadian Medical Association Journal) on Aug. 24, aims to help minimize pain and distress from vaccinations in both children and adults. It outlines a variety of proven interventions that can …

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Largest international study of its kind finds new schizophrenia risk genes

November 21, 2016

Canadian and international scientists have uncovered six new schizophrenia risk genes in the largest study of its kind.

Peter Gilgan Centre for Research and Learning exterior

Standing on the shoulders of giants: how a genetic discovery at SickKids in 1993 continues to inform research and patient care

December 17, 2018

This month marks the 25th anniversary of the discovery of the gene responsible for Wilson disease by scientists at The Hospital for Sick Children (SickKids).

SickKids scientists create new way to classify cancers based on unique hypermutant footprint

October 19, 2017

A game-changing study by SickKids suggests there could be a day where cancers are not classified by their tissue of origin (i.e. brain cancer, breast cancer, colon cancer) but rather by the number and type of genetic mutations they carry. The study …

Two men stand leaning against a railing.

Study finds paramedic care delivered on-scene for 10 to 35 minutes leads to better outcomes for paediatric cardiac arrests

August 25, 2015

A team of researchers led by The Hospital for Sick Children (SickKids) and Lawson Health Research Institute found that survival was the highest, especially among teens, with 10 to 35 minutes on the scene in the care and under the treatment of …

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Turning stem cells into bile duct cells to study ‘disease in a dish’

August 31, 2015

A Toronto team of clinician-scientists and stem cell biologists has developed a powerful new method to generate 3D bile duct structures from human stem cells in order to study and develop new treatments for bile duct diseases.

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SickKids study leads to new practice point for assessing management options for newly diagnosed, typical immune thrombocytopenia

December 20, 2018

Engaging families in shared decision making is essential to examine the benefits and limitations of each treatment option for patients with newly diagnosed, typical immune thrombocytopenia (ITP).

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