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Going ‘outside the box’ to explain different symptoms in people with the same DNA deletion syndrome

November 9, 2020

Even when genetic conditions can be clearly traced to a root cause in the DNA, how those conditions present can vary. A team from the International 22q11.2 Deletion Syndrome Brain Behavior Consortium (IBBC), led by SickKids, discovered they needed …

Dr. Jacob Vorstman

SickKids-led research uncovers potential immune-based therapy for difficult to treat childhood cancers

January 27, 2022

Immune checkpoint inhibitors may help treat some childhood cancers that are resistant to more common cancer treatments such as chemotherapy and radiation therapy.

SickKids study identifies potential predictor for developing cystic fibrosis for children with an inconclusive diagnosis

November 25, 2021

Researchers have identified for the first time a potential biomarker that could be used as a predictive tool in the care of children with CFSPID, an inconclusive cystic fibrosis diagnosis.

SickKids study finds speed limit reduction made Toronto roads safer for pedestrians

February 10, 2020

A unique study design by SickKids researchers is one of few in the world to compare effects of speed limit reduction before and after implementation. 

Bike on a road

SickKids researchers awarded $7.5 million for microbiome and immunology research

February 7, 2020

Researchers from SickKids recently received $7.5 million in funding to study the microbiome and immunology. These team grants were awarded by CIHR and partners in the Canadian Microbiome Initiative 2 and Human Immunology Initiative competitions.

Photo of exterior of Peter Gilgan Centre for Research and Learning

A promising new treatment for recurrent paediatric brain cancer

April 27, 2020

A multi-institutional, international team has developed a novel approach that delivers CAR T cell therapy directly into the cerebrospinal fluid that surrounds a brain tumour.

Photo of researcher in a lab.

SickKids researchers re-engineer toxin to attack previously “undruggable” cancer target

July 10, 2020

Researchers have developed a novel anti-cancer drug protein, which could lead to the development of future therapies for what was previously considered an “undruggable” target.

Illustration of a protein structure showing RRSP in blue and DTB in gold

SickKids scientist Dr. Jean-Philippe Julien named one of Canada’s Top 40 Under 40

November 18, 2021

Dr. Jean-Philippe Julien is one of Canada’s Top 40 Under 40® for 2021, recognized for his contributions to antibody research and commitment to research translation.

Promising new approach to stop growth of brain cancer cells

February 12, 2021

Researchers at SickKids, Princess Margaret Cancer Centre and University of Toronto, showed that chemically inhibiting the enzyme PRMT5 can suppress the growth of glioblastoma cells.

New research reveals impact of COVID-19 pandemic on child and youth mental health

February 26, 2021

SickKids-led study shows troubling impact of COVID-19 pandemic on child and youth mental health.

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