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SickKids

Anica Bulic

Title: Staff Cardiologist, Electrophysiology
Designations: MB B.Ch. BAO
Email: Anica.bulic@sickkids.ca
Fax: 416-813-7547
U of T Positions: Assistant Professor, Department of Paediatrics

Hospital Positions

Project Investigator
Translational Medicine

Biography

Dr. Anica Bulic graduated from the University of Dublin, Trinity College School of Medicine in 2011. She then completed her paediatrics residency at Georgetown University Hospital in Washington, DC, in 2014.

Dr. Bulic continued to do her paediatric cardiology and electrophysiology training at Lucile Packard Children’s Hospital, Stanford University in Palo Alto, California. She joined the Division of Cardiology at The Hospital for Sick Children (SickKids) as Associate Staff in Paediatric Cardiology and Electrophysiology in August 2018. 

Her research interests include pacing in single ventricle congenital heart disease  and Arrhythmias in paediatric heart failure.

Research

Dr. Bulic's current research interests lie in further understanding the effects of electrical dyssynchrony in congenital heart disease, from the protein expression level to clinical outcomes. In doing so, it may identify responders and non-responders to cardiac resynchronization therapy (CRT), a valuable intervention we use to stabilize or improve heart function. In those that are CRT non-responders, AV nodal regeneration may serve as a viable novel biological therapeutic intervention. In collaboration with researchers at MARS, who are attempting to engineer stem-cell derived AV nodal cells, a future research interest of her's is devising a delivery mechanism to repopulate AV nodal cells as a therapy for either medical or post-surgical complete heart block.

Education and Experience

  • 2017–2018: Pediatric Electrophysiology Fellow, Department of Pediatrics, Lucile Packard Children’s Hospital, Standford University, Palo Alto, CA, USA
  • 20142017: Pediatric Cardiology Fellow, Department of Pediatrics, Lucile Packard Children’s Hospital, Standford University, Palo Alto, CA, USA
  • 20112014: Pediatrics Resident, Department of Pediatrics, Georgetown University Hospital, Washington, DC, USA
  • 2006–2011: Bachelor of Medicine, Bachelor of Surgery, Bachelor of Obstetrics. Trinity College Dublin, The University of Dublin, Ireland
  • 2000–2004: Bachelor of Science, Microbiology and Immunology. University of British Columbia, Vancouver, BC, Canada.

Achievements

  • 2018: Medtronic Heart Rhythm Society (HRS) Scholarship Program, recipient, Minneapolis, MN, USA

Publications

  1. Bulic A, Maeda K, Zhang Y, Chen S, McElhinney DB, Dykes JC, Hollander AM, Hollander SA, Murray J, Reinhartz O, Gowan MA, Rosenthal DN, Almond CS. Functional status of United States children supported with a left ventricular assist device at heart transplantation. Journal of Heart Lung Transplantation 2017: 36 (8): pp 890 - 896.
  2. Bulic A, Zimmerman FJ, Ceresnak SR, Shetty I, Motonaga KS, Freter A, Trela AV, Hanisch D, Russo L, Avasarala K, Dubin AM. Ventricular pacing and single ventricles—a bad combination. Heart Rhythm 2017: 14 (6): pp 853 - 857. 
  3. Tse KW, Dang-Lawson M, Lee RL, Vong D, Bulic A, Buckbinder L, Gold MR. B cell receptor-induced phosphorylation of Pyk2 and Focal Adhesion Kinase involves integrins and the Rap GTPases and is required for B cell spreading. Journal of Biological Chemistry 2009: 284: pp 22865 - 22877.
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