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Brian Feldman

Title: Head, Division of Rheumatology 
Designations: MD, M.Sc., FRCPC
Phone: 416-813-7707
Email: brian.feldman@sickkids.ca
Alternate Contact Name: Zahrah Al Dawood
Alternate Phone: 416-813-7654 ext. 207707
Alternate Email: Zahrah.aldawood@sickkids.ca
REACH Profile: Brian Feldman's REACH profile
U of T Positions: Professor, Department of Paediatrics and Institute of Health Policy, Management and Evaluation
Chair Positions: Ho Family Chair in Autoimmune Diseases

Research Positions

Senior Scientist
Child Health Evaluative Sciences

Biography

Dr. Feldman is a clinician scientist and rheumatologist. He holds a general rheumatology clinic, where he sees children with arthritis and other rheumatic complaints, and the childhood dermatomyositis clinic. 

Recognizing the challenges involved in the study of rare disease, Dr. Feldman has worked to improve the tools available to assist in this research. He has worked at developing and refining outcome measurement tools for use in clinical trials and in outcome studies. He has developed innovative methodologies for the study of new therapies (e.g. the Randomized Placebo Phase Design) and refined and tested powerful existing methods (e.g. Bayesian meta-analysis of n-of-1 randomized trials, and causal modeling for longitudinally collected observational data).  

Dr. Feldman has made contributions to the understanding of the prognosis and treatment of juvenile dermatomyositis, the cost-effective prevention of arthropathy in severe hemophilia, the course and outcome of systemic-onset juvenile idiopathic arthritis and juvenile SLE, and the role of fitness, exercise, diet supplementation and sleep in childhood chronic diseases including arthritis, myositis and fibromyalgia.

Education and experience

Degrees

  • 1979–1981: Undergraduate Student, University of Western Ontario, London, Ontario
  • 1981–1985: MD, University of Western Ontario, London, Ontario
  • 1985: L.M.C.C., Medical Council of Canada, Ottawa, Ontario
  • 1990: FRCPC, Royal College of Physicians and Surgeons of Canada
    Ottawa, Ontario
  • 1991–1994: M.Sc., University of Toronto, Toronto, Ontario
  • 1993: FRCPC, Royal College of Physicians and Surgeons of Canada, Ottawa, Ontario

Specialty Training

  • 1985–1986: General Comprehensive Internship, Mount Sinai Hospital, Toronto, Ontario
  • 1986–1989: Paediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario
  • 1989–1990: Associate Chief Resident, The Hospital for Sick Children, Toronto, Ontario

Fellowships

  • 1990–1992: Arthritis Society Clinical Fellow, The Hospital for Sick Children, Toronto, Ontario
  • 1992–1993: Ontario Ministry of Health Research Fellow, The Hospital for Sick Children, Toronto, Ontario

Achievements

  • 2011: Eugenie Stuart Award for Best Instructor.  Faculty of Medicine Department of Health Policy, Management & Evaluation.  University of Toronto
  • 2013–2018: Ho Family Chair in Autoimmune Disease Research
  • 2014: Canadian Rheumatology Association.  Distinguished Investigator Award
  • 2018–2023: Ho Family Chair in Autoimmune Disease Research

  • 1979–1981: University of Western Ontario Tuition Scholarship.
  • 1985: University of Western Ontario Benjamin Weidenbaum and Cecelia Rotstein Scholarship for the second highest standing in the Clinical Clerkship.
  • 1985: University of Western Ontario Dean's Honour List.
  • 1985: University of Western Ontario John C. Rathburn Memorial Prize for highest standing in Pediatrics during the Clinical Clerkship.
  • 1989: Children's Hospital of Eastern Ontario - Core - Resident - Resident Research Award - 3rd Year.
  • 1993: Philip Rosen Research Award. Canadian Rheumatology Association.   
  • 1994: Clinical Epidemiology Research Award.  University of Toronto.
  • 1995: Ontario Ministry of Health Career Scientist.
  • 1998: Post-Graduate Excellence in Teaching, PERLS Lecture Series.
  • 2002–2007: Canada Research Chair in Childhood Arthritis, Tier II,  
  • 2004: Henry Kunkel Young Investigator Award, American College of Rheumatology.
  • 2004: James C. Fallis Teaching Award, Runner-up for presentation at PEM Fellows' Rounds.
  • 2007–2012: Canada Research Chair in Childhood Arthritis Tier II,  
  • 2007: Arthritis Foundation Outstanding Speaker Award 23rd Annual Rheumatology.
  • 2007: Department of Paediatrics Physician Research Award for Scientific Accomplishment.  University of Toronto.

Publications

Sleep and pain in Childhood Arthritis: A crossover randomized control trial comparing adequate and restricted sleep duration, and its impact on pain in adolescents with arthritis. Feldman BM, Beebe D, Dover S, Narang I, Stephens S, Stinson J, Tomlinson G, Weiss S. (CIHR) Canadian Institutes of Health Research. ($256,275 CAD 01/22/2018 – 01/22/2021). PI

UCAN CAN-DU: Canada-Netherlands Personalized Medicine Network in Childhood Arthritis and Rheumatic Diseases.  CIHR/ZonMw/Reumafonds. Co-Principal investigators: Rae S.M. Yeung, Nico Wulffraat, Susanne Benseler, Joost Swart.  Co-investigators:  Claire Bombardier, Joe Cafazzo, Niels Eijkelkamp, Anna Goldenberg, Jaime Guzman, Maarten Ijzerman, Deborah Marshall, Quaid Morris, Berent Prakken, Dave Prowten, Norman Rosenblum, Stephen Scherer, Casper Schoemaker, Jennifer Stinson, Rebecca Ten Cate, George Tomlinson, Marinka Twilt, Sebastian Vastert. ($8,000,000 CAD, 2017 – 2022). COLL



UCAN CURE: Precision decisions for childhood arthritis.  Genome Canada and Ontario Genomics, Large-Scale Applied Research Project Competition, Genomics and Precision Health. Principal Investigator and Project Leader: Rae. S. M. Yeung.  Co-Principal Investigator and Co-Project Leader: Susanne Benseler.  Co-Investigators: Deborah Marshall, Joseph Cafazzo, Stephen Scherer, Anna Goldenberg, Jennifer Stinson, Cindy Guidos, Quaid Morris, Michael Brudno, Maarten Ijzerman, Marvin Fritzler, Nico Wulffraat, Joost Swart, Sebastian Vastert, Marinka Twilt. Genome Canada ($10,000,000 CAD, 2018 – 2022). COLL


Multi-site Randomized Clinical Trial of FIT Teens for Juvenile Fibromyalgia: Kashikar-Zuck S, Stinson J, Feldman BM, Tse S. NIH/ NAIMS, R01 AR070474 ($1,621,318 USD, 06/21/17 - 05/30/22). CoI

Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry (including STOP-JIA, FROST, JIA, JDM, SLE registries and trials). Feldman BM, Cameron B, Hiraki LT, Laxer RM, Levy DM, Schneider S, Silverman ED, Spiegel L, Tse SM, Yeung RSM. Arthritis Foundation. (July 1, 2015-June 30, 2025). Site PI

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