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SickKids

Jean-Philippe Julien

Title: Senior Scientist, Molecular Medicine
Designations: PhD
Phone: 416-813-7654 ext. 309424
Email: jean-philippe.julien@sickkids.ca
Fax: 416-813-5993
U of T Positions: Associate Professor, Departments of Biochemistry and Immunology
Chair Positions: Canada Research Chair, Structural Immunology

Biography

Jean-Philippe Julien received his B.Sc. from McGill University, obtained his PhD from the University of Toronto, and trained as a post-doctoral fellow at The Scripps Research Institute. In Fall 2014, he joined the Molecular Medicine Program at SickKids Research Institute and the Departments of Biochemistry and Immunology at the University of Toronto where he leads a team of multi-disciplinary researchers. His laboratory focuses on the molecular characterization of antibodies by studies of their interactions with cell surface receptors in therapeutic development, and with pathogens guiding vaccine design primarily against Plasmodium falciparum malaria, HIV-1 and COVID-19. Notably, he is a Canada Research Chair in Structural Immunology, a CIFAR Azrieli Global Scholar and a Member of the College of the Royal Society of Canada.

Research

Surface glycoproteins on immune cells often play critical roles that directly influence responses to invading pathogens. A better understanding of their atomic structure and the three-dimensional molecular complexes they form allows us to gain insight into their specific functions. This molecular understanding provides roadmaps for scientists to design improved vaccines against pathogens of global health importance, and treatments in cancer and autoimmune diseases.

Education and experience

  • 2005: B.Sc., Biochemistry, McGill University, Montreal, Quebec
  • 2010: PhD, Biochemistry, University of Toronto, Toronto, Ontario
  • 2010–2014: Post-doctoral Fellow, Integrative Structural and Computational Biology, Scripps Research Institute, USA

Achievements

  • 2020: New Investigator Award, Canadian Society for Immunology
  • 2019: Member of the College of New Scholars, Artists and Scientists of the Royal Society of Canada, Royal Society of Canada 
  • 2019: Azrieli Global Scholar, Canadian Institute for Advanced Research
  • 2019: Ontario Ministry of Research, Innovation and Science Early Researcher Award, Government of Ontario
  • 2017: Young Investigator Excellence Award, Canadian Light Source
  • 2017: Tier 2 Canada Research Chair in Structural Immunology, Canadian Institutes of Health Research 

Publications

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