Audrey Marshall

Director, Cardiac Diagnostic and Interventional Unit (CDIU)

Dr. Marshall is a patient-focused paediatric cardiologist who pursues diagnoses and treatments through interventional catheterization.  Her extensive training and experience have led to her recognition as a leader in the field of invasive cardiology for congenital heart disease, and fetal cardiac intervention.   

Born and raised in the American Midwest, she pursued her education and medical training at institutions including Yale, the University of Pennsylvania, and the Harvard-affiliated Boston Children’s Hospital.  At Boston Children’s, she led the cardiac catheterization laboratory, providing interventional consultation both locally and nationally, and performing 300 procedures a year.  In practice for over 20 years, she has provided cardiac care to some children and their families throughout the course of childhood. She is a mother of three, and an advocate for children with complex healthcare needs.

Education and Experience

• 2020–Present: Section Head, Interventional Cardiology, Hospital for Sick Children, Toronto, ON, Canada
• 2020–Present: Director, Cardiac Diagnostic Interventional Unit (CDIU), Division of Cardiology, Hospital for Sick Children, Toronto, ON, Canada.
• 2020: MPH, Health Policy, Harvard T.H. Chan School of Public Health. Boston, MA, USA.
• 2020–Present: Professor, Department of Paediatrics, University of Toronto, Toronto, ON, Canada
• 2017–2019: Visiting Associate Professor, Department of Pediatrics, Tufts Medical School, Boston, MA, USA.
• 2017–2018: Division Chief, Pediatric Cardiology, Tufts Medical Center / The Floating Hospital for Children, Boston, MA, USA.
• 2017–2017: Professor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
• 2016: Certificate, Advanced Management Program, Harvard Business School, Cambridge, MA, USA.
• 2015–2016: Associate Chief, Clinical Affairs, Department of Cardiology, Boston Children’s Hospital, Boston, MA, USA.
• 2012–2017: Director. Advanced Fetal Care Center, Boston Children’s Hospital, Boston, MA, USA.
• 2009–2017: Associate Professor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
• 2009–2017: Chief, Invasive Cardiology, Boston Children’s Hospital, Boston, MA, USA.
• 2009–2017: Director, Cardiac Catheterization Laboratory, Boston Children’s Hospital, Boston, MA, USA.
• 2004–2009: Assistant Professor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
• 2001–2004: Instructor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
• 1993: MD, Medicine, University of Pennsylvania. Philadelphia, PA, USA.
• 1988: BA, summa cum laude, History, Yale University. New Haven, CT, USA

Research

Dr. Marshall’s current clinical research interests focus on the areas of:

1. Outcomes and complications of interventional catheterization procedures in congenital heart disease (CHD)
2. New technologies and devices used in management of CHD
3. Diagnosis and intervention for prenatally-diagnosed CHD

Dr. Marshall hopes to collaborate with the very active fetal diagnostic and interventional group within the heart centre at SickKids. Also, with her team's participation in a North American registry of paediatric interventional catheterization procedures, she intends to work with colleagues at other centers reporting multi-center outcomes of the procedures included. With regard to new devices/technologies, Dr. Marshall aims to resume investigation of an implantable hemodynamic monitoring system which would allow real-time availability of invasive circulatory measurements in the management of patients with CHD. This is a device that has won regulatory approval for use in heart failure management but has not yet been adopted for use in paediatric patients.

Achievements

• 2021: Co-Chair, American Academy of Pediatrics Section on Cardiology and Cardiovascular Surgery, Committee on Advocacy and Policy.
• 2020: Visiting fellow, Massachusetts Health Policy Commission
• 2018: American Board of Pediatrics: Cardiology Sub-board. American Board of Pediatrics.
• 2014: Society of Pediatric Cardiology Training Program Directors, American College of Cardiology, American Academy of Pediatrics, American Heart Association Joint Task Force on Training Guidelines for Pediatric Cardiology Fellowship Programs.
• 2012: International Congress Program Planning Committee. Annual Meeting of the American College of Cardiology.
• 2007: 11^th class of the Henry Crown Fellowship of the Aspen Institute
• 2003: Course Director, International Meeting on Prenatal Cardiac Interventions, Boston Fetal Cardiac Program, Boston, MA, USA

1. Marshall AC, Tworetzky W, Bergersen L, McElhinney DB, Benson CB, Jennings RW, Wilkins-Haug LE, Marx GR, Lock JE. Aortic valvuloplasty in the fetus: technical characteristics of successful balloon dilation. The Journal of Pediatrics 2005;147(4):535-9. 
2. Esch JJ, Shah PB, Cockrill BA, Farber HW, Landzberg MJ, Mehra MR, Mullen MP, Opotowsky AR, Waxman AB, Lock JE, Marshall AC.  Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: Initial clinical experience  The Journal of Heart and Lung Transplantation 2013; 32:  381-7. 
3. Callahan R, Kieran MW, Baird CW, Colan SD, Gauvreau K, Ireland CM, Marshall AC, Sena LM, Vargas SO, Jenkins KJ.  Adjunct Targeted Biologic Inhibition Agents to Treat Aggressive Multivessel Intraluminal Pediatric Pulmonary Vein Stenosis.  The Journal of Pediatrics. 2018; 198:  29-35. 
4. Callahan R, Lock JE, Shah PB, Marshall AC. Transcatheter Intervention of Coronary Obstructions in Infants, Children, and Young Adults.  Pediatric Cardiology 2018 Oct; 39(7):1299-1307. 1894. Epub 2018 May 9.
5. Przybylski R, Hedequist DJ, Nasr VG, McCann ME, Brustowicz RM, Emans JB, Marshall AC, Brown DW.  Adverse perioperative events in children with complex congenital heart disease undergoing operative scoliosis repair in the contemporary era. Pediatric Cardiology 2019 Oct; 40(7): 1468-1475.