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Christopher Macgowan

Title:
Senior Scientist, Translational Medicine
Designations:
PhD
Phone:
416-813-1069
Email:
christopher.macgowan@sickkids.ca
Alternate Contact Name:
Cristina Millan
Alternate Phone:
416-813-8593
Alternate Email:
cristina.millan@sickkids.ca
U of T Positions:
Associate Professor, Department of Medical Biophysics

Research Positions

Director of the Research MRI Core Facility

Biography

Christopher Macgowan received his graduate training from the Department of Medical Biophysics at the University of Toronto, where he received an M.Sc. and a PhD on the topic of blood flow measurement using magnetic resonance imaging (MRI).

He was recruited to The Hospital for Sick Children (SickKids) in 2000 to develop a research program in cardiovascular imaging, and is now a Senior Scientist in the Translational Medicine program and the Department of Diagnostic Imaging at SickKids. He is also an Associate Professor in the Departments of Medical Biophysics and Medical Imaging at the University of Toronto.

Research

Macgowan’s research involves the development of new magnetic resonance imaging (MRI) methods to improve the detection and evaluation of cardiovascular disease in children. In particular, he is interested in the fast measurement of blood flow and vascular function in congenital heart disease, and the translation of these methods into clinical practice.

Recent work in his lab has focused on accelerated imaging and advanced reconstruction methods, including motion correction, to study cardiovascular physiology in the human fetus and newborn child while avoiding the need for sedation.

Education

  • 1989–1993: B.Sc., Physics (Honours), University of British Columbia, Vancouver, BC, Canada.
  • 1993–1995: M.Sc., Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • 1995–2000: PhD, Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

Publications

  1. Roy CW, Seed M, Kingdom JC, Macgowan CKMotion compensated cine CMR of the fetal heart using radial undersampling and compressed sensing J. Cardiov. Magn. Reson. 19:29 (2017)
  2. Sun L, Macgowan CK, Sled JG, Manlhiot C, Porayette P, Grosse-Wortmann L, Jaeggi E, McCrindle BW, Kingdom J, Hickey E, Miller S, Seed M. Reduced Fetal Cerebral Oxygen Consumption Is Associated With Smaller Brain Size in Fetuses With Congenital Heart DiseaseCirculation 131, 1313-1323 (2015)
  3. Seed M, van Amerom JFP, Yoo SJ, Al Nafisi B, Grosse-Wortmann L, Jaeggi E, Jansz MS, Macgowan CKFeasibility of Quantification of the Distribution of Blood Flow in the Normal Human Fetal Circulation Using CMR: A Cross-Sectional Study J. Cardiov. Magn. Reson. 14 (2012)
  4. Jansz MS, Seed M, van Amerom JFP, Wong D, Grosse-Wortmann L, Yoo SJ, Macgowan CKMetric Optimized Gating for Fetal Cardiac MRI. Magn. Reson. Med. 64(5): 1304-1314 (2010)
  5. Macgowan CK, Wood ML. Phase-Encode Reordering to Minimize Errors Caused by Motion. Magn. Reson. Med. 35, 391-398 (1996)

View a full list of Christopher Macgowan's publications

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