Andrew Paterson

Dr. Paterson received a medical degree from the University of Glasgow in 1995 and from 1996 to 2000. He was a postdoctoral fellow at the University of Toronto.

From 2000 to 2001, he was a Research Associate at The Centre for Applied Genomics at The Hospital for Sick Children (SickKids). In 2001, he became a Scientist in Genetics & Genome Biology at SickKids Research Institute and in 2008 he was promoted to Senior Scientist.

Research

Dr. Paterson’s work identifies genetic variations that are statistically associated with variation in both quantitative traits as well as specific diseases in humans. He focuses on traits related to diabetes, including kidney disease, eye disease, heart disease and nerve disease.

His team is also identifying genetic variants associated with measures of glycemia, including skin fluorescence. Dr. Paterson is involved in a number of projects where new methods for genetic studies are being developed.

Education and experience

• 2008–Present: Senior Scientist, Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON
• 2008–2014: Associate Professor, Biostatics & Psychiatry, University of Toronto, Toronto, ON
• 2001–2008: Scientist, Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON
• 2008–Present: Full Member, Institute of Medical Science, Medicine, University of Toronto, Toronto, ON
• 2001–2007: Associate Member, Institute of Medical Science, Medicine, University of Toronto, Toronto, ON
• 2000–2001: Postdoctorate, Research Associate, Genetics of Complex Disease, The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON
• 1997–2000: CIHR Fellowship, Genetics of complex Disease, University of Toronto, Toronto, ON
• 1996–1997: Postdoctorate, Fellow, Genetics of complex disease, Clarke Institute of Psychiatry, Toronto, Ontario
• 1988–1995: Doctorate, MB Ch.B. – MD, Medicine, University of Glasgow, Scotland, UK
• 1991–1993: Bachelor’s Faculty of Science, Neuroscience, University of Glasgow, Scotland, UK

Achievements

• 2014–2016: International Genetic Epidemiology Society, Board of Directors
• 2014: ‘Optimal Strategies for Complex Genetic Traits’ The Kenneth M. Brinkhous Memorial plenary Lecture, International Society on Thrombosis and Haemostasis, Scientific and Standardization Committee. 24 June 2014, Milwaukee, IL.
• 2014: ‘The genetics of risk factors and long-term complications of Type 1 Diabetes’ Benjamin F. Stapleton Jr. Lecture on the Genetics of Diabetes, Human Medical Genetics and Genomics Program, School of Medicine, University of Colorado, CO.
• 2009–2013: International Genetic Epidemiology Society, Publications Committee
• 2013–2017: International Genetic Epidemiology Society, Scientific Program Committee
• 2002–2012: Canada Research Chair Tier II– Genetics of Complex Disease American Diabetes Association Genetics program committee member, 2012 annual scientific meeting.
• 2012–2013: Genetic Analysis Workshop 18, Summary Papers editor

1. Sun L, Wang Z, Lu T, Manolio TA, Paterson AD. eXclusionarY: 10 years later, where are the sex chromosomes in GWASs? Am J Hum Genet. 2023 Jun 1;110(6):903-912. doi: 10.1016/j.ajhg.2023.04.009. PMID: 37267899
2. Vollenbrock CE, Roshandel D, van der Klauw MM, Wolffenbuttel BHR, Paterson AD. Genome-wide association study identifies novel loci associated with skin autofluorescence in individuals without diabetes. BMC Genomics. 2022 Dec 19;23(1):840. doi: 10.1186/s12864-022-09062-x. PMID: 36536295
3. Wang Z, Sun L, Paterson AD. Major sex differences in allele frequencies for X chromosomal variants in both the 1000 Genomes Project and gnomAD. PLoS Genet. 2022 May 31;18(5):e1010231. doi: 10.1371/journal.pgen.1010231. eCollection 2022 May. PMID: 35639794
4. Gagliano Taliun SA, Sulem P, Sveinbjornsson G, Gudbjartsson DF, Stefansson K, Paterson AD, Barua M. GWAS of Hematuria. Clin J Am Soc Nephrol. 2022 May;17(5):672-683. doi: 10.2215/CJN.13711021. Epub 2022 Apr 26. PMID: 35474271
5. Bebu I, Keshavarzi S, Gao X, Braffett BH, Canty AJ, Herman WH, Orchard TJ, Dagogo-Jack S, Nathan DM, Lachin JM, Paterson AD; DCCT/EDIC Research Group. Genetic Risk Factors for CVD in Type 1 Diabetes: The DCCT/EDIC Study. Diabetes Care. 2021 Jun;44(6):1309-1316. doi: 10.2337/dc20-2388. Epub 2021 Apr 21. PMID: 33883194

See a full list of Dr. Peterson's publications.