Ryan Yuen

Education and experience

• 2022–present: Senior Scientist, Genetics and Genome Biology, SickKids Research Institute, Toronto, ON
• 2017–2022: Scientist, Genetics and Genome Biology, SickKids Research Institute, Toronto, ON
• 2017–present: Assistant Professor, Molecular Genetics, University of Toronto, Toronto, ON
• 2014–2017: Research Associate, Genetics and Genome Biology, SickKids, Toronto, ON 
• 2011–2014: Post-doctoral Fellow, Genetics and Genome Biology, SickKids, Toronto, ON
• 2007–2011: PhD, Medical Genetics, University of British Columbia, Vancouver, BC

1. Dolzhenko E*, Bennett MF*, Richmond PA*, Trost B, Chen S, van Vugt JJFA, Nguyen C, Narzisi G, Gainullin VG, Gross A, Lajoie B, Taft RJ, Wasserman WW, Scherer SW, Veldink JH, Bentley DR, Yuen RKC*, Bahlo M*, Eberle MA*. (2020) ExpansionHunter Denovo: A computational method for locating known and novel repeat expansions in short-read sequencing data. Genome Biology. Apr 28;21(1):102. *Equal contribution.
2. Yuen RKC, Merico D, Bookman M, L Howe J, Thiruvahindrapuram B, Patel RV, Whitney J, Deflaux N, Bingham J, Wang Z, Pellecchia G, Buchanan JA, Walker S, Marshall CR, Uddin M, Zarrei M, Deneault E, D'Abate L, Chan AJ, Koyanagi S, Paton T, Pereira SL, Hoang N, Engchuan W, Higginbotham EJ, Ho K, Lamoureux S, Li W, MacDonald JR, Nalpathamkalam T, Sung WW, Tsoi FJ, Wei J, Xu L, Tasse AM, Kirby E, Van Etten W, Twigger S, Roberts W, Drmic I, Jilderda S, Modi BM, Kellam B, Szego M, Cytrynbaum C, Weksberg R, Zwaigenbaum L, Woodbury-Smith M, Brian J, Senman L, Iaboni A, Doyle-Thomas K, Thompson A, Chrysler C, Leef J, Savion-Lemieux T, Smith IM, Liu X, Nicolson R, Seifer V, Fedele A, Cook EH, Dager S, Estes A, Gallagher L, Malow BA, Parr JR, Spence SJ, Vorstman J, Frey BJ, Robinson JT, Strug LJ, Fernandez BA, Elsabbagh M, Carter MT, Hallmayer J, Knoppers BM, Anagnostou E, Szatmari P, Ring RH, Glazer D, Pletcher MT, Scherer SW. (2017). Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder. Nature Neuroscience. Apr;20(4):602-611.
3. Yuen RKC*†, Merico D*, Cao H*, Pellecchia G, Alipanahi B, Thiruvahindrapuram B, Tong X, Sun Y, Cao D,  Zhang T, Wu X, Jin X, Zhou Z, Liu X, Nalpathamkalam T, Walker S, Howe JL, Wang Z, MacDonald JR, Chan A, D’Abate L, Deneault E, Siu MT, Tammimies K, Uddin M, Zarrei M, Wang M, Li Y, Wang J, Wang J, Yang H, Bookman M, Bingham J, Gross SS, Loy D, Pletcher M, Marshall CR, Anagnostou E, Zwaigenbaum L, Weksberg R, Fernandez BA, Roberts W, Szatmari P, Glazer D, Frey BJ, Ring RH†, Xu X†, Scherer SW†. (2016). Genome-wide characteristics of de novo mutations in autism. NPJ Genomic Medicine. Aug 3;1:160271-1602710. *Equal contribution. †Co-correspondence.
4. Yuen RKC, Thiruvahindrapuram B, Merico D, Walker S, Tammimies K, Hoang N, Chrysler C, Nalpathamkalam T, Pellecchia G, Liu Y, Gazzellone M, D’Abate L, Deneault E, Howe JL, Liu RSC, Thompson A, Zarrei M, Uddin M, Marshall CR, Ring RH, Zwaigenbaum L, Ray P, Weksberg R, Carter M, Fernandez BA, Roberts W, Szatmari P, Scherer SW. (2015). Whole-genome sequencing of quartet families with Autism Spectrum Disorder. Nature Medicine. Feb; 21(2):185-91.
5. Xiong HY*, Alipanahi B*, Lee LJ*, Bretschneider H, Merico D, Yuen RKC, Hua Y, Gueroussov S, Najafabadi HS, Bretschneider H, Hughes TR, Morris Q, Barash Y, Krainer AR, Jojic N, Scherer SW, Blencowe BJ, Frey BJ. (2015). The splicing code reveals new insights into the genetic determinants of disease. Science. Jan; 347(6218):1254806. *Equal contribution. 

See a full list of Ryan Yuen's publications