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Neurosciences & Mental Health

Neurosciences & Mental Health

Head: Dr. Donald Mabbott

Research in the Neurosciences & Mental Health program aims to uncover the mechanisms regulating development and plasticity of complex neural systems in animal models and humans by applying a wide spectrum of approaches including molecular genetics, electrophysiology, behavior, cognition and neuroimaging. Our ultimate goal is to translate discoveries to innovative solutions for mitigating and curing brain diseases in children.

Some current NMH research studies:

  • Developmental and pathological neuroplasticity and neuron-glia interactions
  • Development of sensory systems and pain
  • Cognitive function and dysfunction in model organisms and children
  • Inherited and acquired central nervous system disorders in model organisms and children
  • Functional neuro-imaging and cognitive neuroscience in children
  • Complex neurogenetics disorders, such as, ADHD, autism and learning disabilities
  • Design of (EMPOWER®) program to address the core cognitive barriers that prohibit children from becoming successful readers 

Psychiatric disorders share an underlying genetic basis, says landmark paper with U of T research

Nine researchers from the University of Toronto's Faculty of Medicine contributed to a major international study, published in the journal Science, showing the underlying genetic similarities between mental illnesses like schizophrenia and bipolar disorder. Read the full story here

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Did You Know?

The International Union of Basic and Clinical Pharmacology (IUPHAR) has formulated nomenclature recommendations for ligand-gated ion channels to help standardize classification of the major receptor and ion channel systems in the human genome. Read more